Blog, News and Events

15 September 2025

Exhibition at EuroTox 2025

The Congress of the European Societies of Toxicology is organizing EuroTox 2025 to focus on this year's theme “Toxicology addresses Society’s real-life risks for sustainable health and well-being”. The 2025 program will focus on cutting-edge scientific breakthroughs and interdisciplinary collaboration. Emerging technologies and methodologies such as humanized liver applications in toxicology will be highlighted, while fostering discussions on public health safety and environmental sustainability. PhoenixBio is excited to be sponsoring a booth and attending the EuroTox 2025 in person at the Megaron Concert Hall in Athens, Greece from September 14th - 17th, 2025. Meet with our team at Booth #A17 to learn more about PhoenixBio's capabilities and how we can help you advance and deliver tomorrow’s technologies.

Events

11 September 2025

Cutting Edge Gene Editing in Primary Human Hepatocytes

Gene editing promises cures for a wide range of diseases. Zinc-finger nucleases (ZFNs) were developed as the first programmable editors in the early 2000s, followed by TALENs (Transcription Activator Like Effector Nucleases) about a decade later[1]. However, it was the discovery and application of easy to use CRISPR/Cas9 gene editing methods, that sparked a flurry of new activity since 2013. New gene editing methods that build on this platform continue to be a hot area of research, with the goal of developing techniques that increase specificity and circumvent the need for double-stranded breaks (DBSs) in order to reduce off-target effects and minimize safety concerns[2]. Moreover, increasing the size of sequences that can be modified, and improving editing efficiency in non-dividing cells are also areas of great interest.

Blog, PXB-cells

19 August 2025

Advancing the Development of Safe & Effective LNP-Delivered Therapies using Humanized Liver Models

Oligonucleotide therapeutics have shown promise as a diverse treatment option for a wide range of diseases. Developing successful oligonucleotide therapeutics depends on being able to efficiently deliver the therapeutic to the target cells.

PXB-mouse, Blog

18 August 2025

Bridging the translational gap: Humanized Liver models as predictive tools for RNA therapeutic success

The field of RNA therapeutics, with its potential for treating a wide range of diseases, continues to experience rapid growth and attracts significant investment. According to the American Society of Gene & Cell Therapy (ASGCT), as of Q1 2025, 35 RNA therapies have been approved globally and another 1,298 are currently in development (between preclinical and pre-registration stages) [1].

PXB-mouse, Blog

17 June 2025

From modeling disease to supporting translational preclinical studies: a year in humanized liver model research

PXB-mice and PXB-cells offer a highly physiologically relevant liver model for in vivo and in vitro research, respectively. They have been shown to have versatile applications in studies, ranging from hepatitis B virus (HBV) infection modeling to epigenetic research. In this round-up, we look back on the past year to showcase some of the most interesting and impactful research utilizing PXB-mice and/or PXB-cells, spanning disease modeling, drug metabolism, and epigenetic editing.

Blog

10 June 2025

Exhibition at the MPS World Summit 2025

PhoenixBio is excited to be sponsoring a booth and attending the Microphysiological Systems World Summit 2025 (MPS 2025) in person in Brussels, Belgium from June 10th - 13th, 2025. Meet with our team at Booth #110 to learn more about PhoenixBio's capabilities and how we can help you improve lives through tomorrow's technologies.

Events

12 May 2025

Exhibition at the American Society of Cell & Gene Therapy 2025 Meeting

PhoenixBio is excited to be sponsoring a booth and attending the American Society for Gene & Cell Therapy (ASGCT 2025) in person in New Orleans, USA from May 13th - 17th, 2025. Meet with our team at Booth #1444 to learn more about PhoenixBio's capabilities and how we can help you improve lives through safe and effective cell and gene therapies.

Events

7 May 2025

Exhibition at the ISCT 2025

PhoenixBio is excited to be sponsoring a booth and attending the International Society for Cell & Gene Therapy (ISCT 2025) in person in New Orleans, USA from May 7th - 10th, 2025. Meet with our team at Booth #223 to learn more about PhoenixBio's capabilities and how we can help you improve lives through safe and effective cell and gene therapies.

Events