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We are revolutionizing the translational potential of animal models in preclinical research. Discover the latest articles and news about our recent activities.

Humanized Liver Models: Revolutionizing RNA Therapeutic Development

The rapid growth of RNA therapeutics, including siRNA and mRNA, is transforming the pharmaceutical and medical landscape, offering unprecedented potential for treating diseases ranging from viral infections to metabolic disorders. Despite this promise, translating these groundbreaking treatments from the lab to the clinic is fraught with challenges.

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Humanized Liver PXB-Mouse

Newsweek Feature: Pioneering Drug Development with Human Liver Models

Breaking News: Revolutionizing Pharmaceutical Innovation with Japan’s PhoenixBio In the realm of pharmaceutical innovation, a new dawn arises with Japan's PhoenixBio leading the charge. With a groundbreaking article recently published, PhoenixBio introduces cutting-edge human liver models boasting an astonishing 90% and higher human hepatocyte composition, redefining drug testing worldwide while upholding the highest ethical standards.

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Newsweek article on PhoenixBio

Unlocking the Future of AAV-Based Gene Therapies

The promise of adeno-associated virus (AAV) vector-based gene therapies is undeniable. These therapies have already demonstrated potential in treating conditions like spinal muscular atrophy, retinal dystrophy, and hemophilia B, with the FDA approving three treatments as of early 2023. Yet, despite these successes, many promising therapies fail during clinical trials.

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Liver Gene Therapy

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