The aim of this pre-clinical study is to evaluate the activity of VIR-2218 and VIR-3434 as monotherapy and in combination in two well-established mouse models of HBV infection: C57BL/6 mice transduced with adeno-associated virus 8-hepatitis B virus (AAV8-HBV) (genotype D) and human liver-chimeric PXB-mice infected with HBV (genotype C)

Authors: Julia Noack, Jonathan Gall, Hasan Imam, Yesseinia Anglero-Rodriguez, Vasant Jadhav, Michael A. Schmid, Anna I. Bakardjiev, Lisa A. Purcell, Christy Hebner, Florian A. Lempp

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